Fat-soluble vitamins

FIADEK® is classified as Food for Special Medical Purposes appropriate for Cystic Fibrosis treatment. FIADEK® contains concentrated amounts of fat-soluble vitamins, essential in our diet for a normal function of the body.

Formula of fat-soluble vitamins A, D, E and K with Vit. C, E and Zinc as antioxidants. Based on the international guidelines for vitamin supplementation in patients affected by Cystic Fibrosis.

  • FIADEK® provides the fat-soluble vitamins in ONE DAILY TAKE
  • More than 5 years preventing Severe Malnutrition in Children and Adults with F.Q.
  • FIADEK® increases adherence to treatment
  • FIADEK® allows greater therapeutic compliance
  • FIADEK® is the brand of Fat-soluble Vitamins in C.F.

Plasma levels of fat-soluble vitamins are generally below normal, even when the recommended doses of supplements are met, because fat absorption is often compromised.

Vitamin E deficiency is especially common, so it is recommended that all patients are supplemented.

Patients with E.P.I. must be supplemented with vitamins A and D.

Routine vitamin K supplementation is unnecessary, although in young children or with liver disease there may be deficit.

The levels of water-soluble vitamins are, generally, normal.

The prognosis of affected patients with Cystic Fibrosis can be negatively affected by Nutritional Deficiencies and problems in the Absorption of nutrients:

Vitamin – A
It´s lack can cause: loss of visual acuity and alteration of the Respiratory Mucociliary Epithelium with the risk of cell tissue deterioration.

Vitamin – D
Approximately 35% of children with C.F. have a significant deficiency since birth. The lack of Vitamin D reduces Bone Calcification, and can also cause: Rickets and Growth Deficit in children and Osteoporosis and Osteomalacia in Adults.

Vitamin – E
The deficiency of this Vitamin has been found in up to 50% of patients diagnosed by Neonatal Screening. Vitamin E protects the Cell Membrane by counteracting the effect of Free Radicals.

Vitamin – K
This Vitamin plays a fundamental role in Bone Health and in the Prevention of Hemorrhagic Manifestations.

Which is the difference between Fat-soluble and Water-soluble Vitamins ?

Water-soluble vitamins dissolve in water and are not stored in the body, so the body has the responsibility to use them immediately. The amount of vitamins that not needed, are eliminated through urine, so it is generally recommended to take them daily to maintain levels balanced.

Fat-soluble vitamins, on the other hand, dissolve in fat, including oil and are stored in the tissue. They are especially indicated for patients with Cystic Fibrosis, since they usually have plasma levels of these vitamins below normal. These vitamins are essential for our body to function properly, and also have an influence in our physical and mental health. It should be noted that the excess intake of fat-soluble vitamins can be toxic, which reaffirms the importance of being controlled by a specialist.

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